Associate Principal Scientist, In Vivo Pharmacology

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From MSD’s original posting

Job Description We are recruiting an Associate Principal Scientist to join our In Vivo Pharmacology team located at our South San Francisco research laboratories. This role will focus on developing in vivo pharmacology strategy and pharmacodynamics (PD) and efficacy models for cardiometabolic, renal, and respiratory diseases, as well as establishing quantitative PK/PD relationship and preclinical proof-of-concept. Working with a team of multidisciplinary scientists, this individual will apply knowledge of translational animal models, in vivo technology platforms, and quantitative pharmacology to advance pipeline of therapeutic programs. The ideal candidate will possess deep scientific and technical expertise as well as strong leadership and communication skills to manage complex projects both internally and with external partners. Key Responsibilities: • Drive in vivo pharmacology strategy: Act as a scientific leader, defining and executing in vivo model development and pharmacology strategy for preclinical programs. Design and execute target engagement, PD, and efficacy studies, ensuring high scientific and ethical standards. Provide expert troubleshooting for complex study design…